SwissBioisostere is back—with a major ChEMBL 36 update! The database now offers twice as much data: 130 million datapoints covering 43 million unique molecular replacements. Thank you for your patience while we removed our ChemAxon dependencies.
Database is queried.
Loading time is depending on the number of replacements observed. A typical query takes between a couple of seconds to a minute.
We are analysing 65.7 million datapoints. Please be patient.
I want to search for possible replacements of a fragment
I want to get information on a given molecular replacement
Fragment 1
Fragment 2
Fill with an example: side chain, linker, scaffold